UF 010 | B1146

UF 010 is class I HDAC inhibitor that displays >6- fold selectivity over other HDACs. It has an IC₅₀ value of 0.06, 0.1, and 1.5 μM for HDACs 3, 2, 1 and 8 respectively. In vitro experimental data shows accumulation of acetylated histones in HCT116 cells. UF 010 is known to arrest cells at G1/S transition inhibiting proliferation of various cancer cell lines.

UF 010 is class I HDAC inhibitor that displays >6- fold selectivity over other HDACs. It has an IC₅₀ value of 0.06, 0.1, and 1.5 μM for HDACs 3, 2, 1 and 8 respectively. In vitro experimental data shows accumulation of acetylated histones in HCT116 cells. UF 010 is known to arrest cells at G1/S transition inhibiting proliferation of various cancer cell lines.

B1146 | UF 010 DataSheet

Alternate Name/Synonyms: 4-Bromo-N'-butylbenzohydrazide

Appearance: White Solid

Formulation: N/A

CAS Number: 537672-41-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₅BrN₂O

Molecular Weight: 271.15

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO(>25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: UF 010 is potent and selective class I HDAC inhibitor

MDL Number:

PubChem CID: 4596836

SMILES: CCCCNNC(=O)C1=CC=C(C=C1)Br

InChi: 1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)

InChi Key: BVQCFCYPFJOOAV-UHFFFAOYSA-N