URB597 | B2613

URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). FAAH is the enzyme that hydrolyzes anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 displays both antinociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds.

URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). FAAH is the enzyme that hydrolyzes anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 displays both antinociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds.

B2613 | URB597 DataSheet

Alternate Name/Synonyms: KDS-4103, (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate

Appearance: Crystalline solid

Formulation:

CAS Number: 546141-08-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₂N₂O₃

Molecular Weight: 338.4

Cell-Permeable?: True

Purity: ≥98%

Solubilities: ~10 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: a potent and selective inhibitor of fatty acid amide hydrolase (FAAH)

MDL Number:

PubChem CID: 1383884

SMILES: O=C(NC1CCCCC1)Oc1cccc(c1)c1cccc(c1)C(=O)N

InChi: InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)

InChi Key: ROFVXGGUISEHAM-UHFFFAOYSA-N