Description
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). FAAH is the enzyme that hydrolyzes anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 displays both antinociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds.
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). FAAH is the enzyme that hydrolyzes anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 displays both antinociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds.
Alternate Name/Synonyms: KDS-4103, (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate
Appearance: Crystalline solid
Formulation:
CAS Number: 546141-08-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₂N₂O₃
Molecular Weight: 338.4
Cell-Permeable?: True
Purity: ≥98%
Solubilities: ~10 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: a potent and selective inhibitor of fatty acid amide hydrolase (FAAH)
MDL Number:
PubChem CID: 1383884
SMILES: O=C(NC1CCCCC1)Oc1cccc(c1)c1cccc(c1)C(=O)N
InChi: InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
InChi Key: ROFVXGGUISEHAM-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |