Valganciclovir Hydrochloride | B2708

Valganciclovir is a L-valyl ester prodrug of ganciclovir (Cat. No. 1918), an antiviral agent used for the treatment of HIV associated retinitis and for the prevention of post-transplant cytomegalovirus (CMV) infections. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.

Valganciclovir is a L-valyl ester prodrug of ganciclovir (Cat. No. 1918), an antiviral agent used for the treatment of HIV associated retinitis and for the prevention of post-transplant cytomegalovirus (CMV) infections. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.

B2708 | Valganciclovir Hydrochloride DataSheet

Alternate Name/Synonyms: Valcyte,2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride hydrate

Appearance: Crystalline solid

Formulation:

CAS Number: 175865-59-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₂₂N₆O₅·HCl

Molecular Weight: 390.83

Cell-Permeable?: TRUE

Purity: ≥ 98% by titration

Solubilities: ~20 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An antiviral agent

MDL Number: MFCD08460118

PubChem CID: 135413534

SMILES: CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N.Cl

InChi: InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H/t8?,9-;/m0./s1

InChi Key: ZORWARFPXPVJLW-MTFPJWTKSA-N