Voglibose | B2111

Voglibose is a competitive α-glucosidase inhibitor (IC₅₀ = 5.6 µM). It delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase, isomaltase, and sucrase with IC₅₀ values of 0.18, 5.2, and 0.37 µM, respectively. Voglibose is also known to increase glucagon-like peptide 1 release.

Voglibose is a competitive α-glucosidase inhibitor (IC₅₀ = 5.6 µM). It delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase, isomaltase, and sucrase with IC₅₀ values of 0.18, 5.2, and 0.37 µM, respectively. Voglibose is also known to increase glucagon-like peptide 1 release.

B2111 | Voglibose DataSheet

Alternate Name/Synonyms: 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol, N-(1,3-Dihydroxyprop-2-yl)valiolamine; AO-128

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 83480-29-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₀H2₂₁NO₇

Molecular Weight: 267.3

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (~10 mg/ml) or H₂O (~20 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A competitive α-glucosidase inhibitor

MDL Number: MFCD00865496

PubChem CID: 444020

SMILES: C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO

InChi: InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1

InChi Key: FZNCGRZWXLXZSZ-CIQUZCHMSA-N