Description
WAY-170523 is a potent and selective inhibitor of MMP-13 (IC₅₀ = 17 nM). Inhibits MMP-9, TACE and MMP-1 only at higher concentrations (IC₅₀ values of 945, >1000 and >10,000 nM, respectively).
WAY-170523 is a potent and selective inhibitor of MMP-13 (IC₅₀ = 17 nM). Inhibits MMP-9, TACE and MMP-1 only at higher concentrations (IC₅₀ values of 945, >1000 and >10,000 nM, respectively).
Alternate Name/Synonyms: N-[2-[4-[[[2-[(Hydroxyamino)carbonyl]-4,6-dimethylphenyl](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]-2-benzofurancarboxamide
Appearance: White solid
Formulation: N/A
CAS Number: 307002-73-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₃H₃₁N₃O₇S
Molecular Weight: 613.68
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective inhibitor of MMP-13 inhibitor
MDL Number: MFCD09753279
PubChem CID: 9830392
SMILES: CC1=CC(=C(C(=C1)C(=O)NO)N(CC2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)OCCNC(=O)C4=CC5=CC=CC=C5O4)C
InChi: InChI=1S/C33H31N3O7S/c1-22-18-23(2)31(28(19-22)32(37)35-39)36(21-24-8-4-3-5-9-24)44(40,41)27-14-12-26(13-15-27)42-17-16-34-33(38)30-20-25-10-6-7-11-29(25)43-30/h3-15,18-20,39H,16-17,21H2,1-2H3,(H,34,38)(H,35,37)
InChi Key: FARMEEAGJWMFSZ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |