Description
Wogonoside is a flavonoid with antioxidant, anti-cancer and anti-angiogenic activity. Wogonoside inhibits the growth of U937 and HL-60 cells cells. It arrests the cell cycle at the G0/G1 phase and decreases the G2/M and S phases in these cells in a dose dependent manner at concentrations of 50 μM, 100 μM, and 150 μM. It inhibits LPS-induced angiogenesis by inhibiting the toll-like receptor 4 upregulation.
Wogonoside is a flavonoid with antioxidant, anti-cancer and anti-angiogenic activity. Wogonoside inhibits the growth of U937 and HL-60 cells cells. It arrests the cell cycle at the G0/G1 phase and decreases the G2/M and S phases in these cells in a dose dependent manner at concentrations of 50 μM, 100 μM, and 150 μM. It inhibits LPS-induced angiogenesis by inhibiting the toll-like receptor 4 upregulation.
Alternate Name/Synonyms: Wogonin 7-O-glucuronide; Oroxindin; (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)oxyoxane-2-carboxylic acid; 5,7-dihydroxy-8-methoxyflavone 7-O-beta-D-glucuronide; 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid; Glychionide B; Wogonin 7-O-β-D-Glucuronopyranoside
Appearance: Solid
Formulation:
CAS Number: 51059-44-0
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₂₂H₂₀O₁₁
Molecular Weight: 460.39
Cell-Permeable?: True
Purity: ≥95%
Solubilities: Soluble in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: Flavonoid with antioxidant, anti-cancer and anti-angiogenic activity
MDL Number:
PubChem CID: 3084961
SMILES: COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)OC4C(C(C(C(O4)C(=O)O)O)O)O
InChi: InChI=1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1
InChi Key: LNOHXHDWGCMVCO-NTKSAMNMSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
RT |
Shelf Life: |
36 months |