Y15 | B1252

Y15 is a selective focal adhesion kinase (FAK) inhibitor preventing FAK autophosphorylation at IC₅₀ of 1 μM. It does not have any significant activity against a range of other kinases like EGFR, PDGFR, and IG-RI. Y15 has shown to promote cell detachment inhibiting cell adhesion in in vitro experiments, shows antiproliferative activity in variety of tumor cell lines. In vivo it has shown to inhibit the proliferation in breast cancer cells.

Y15 is a selective focal adhesion kinase (FAK) inhibitor preventing FAK autophosphorylation at IC₅₀ of 1 μM. It does not have any significant activity against a range of other kinases like EGFR, PDGFR, and IG-RI.

B1252 | Y15 DataSheet

Alternate Name/Synonyms: 1,2,4,5-benzenetetramine, tetrahydrochloride

Appearance: Light Yellow Solid

Formulation: N/A

CAS Number: 4506-66-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Yes

Molecular Formula: C₆H₁₀N₄•4HCl

Molecular Weight: 284.01

Cell-Permeable?: Yes

Purity: ≥95%

Solubilities: DMSO (>20 mg/ml) or (H₂O (>15 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A selective focal adhesion kinase (FAK) inhibitor having antiproliferative activity

MDL Number: MFCD00012970

PubChem CID: 78260

SMILES: C1=C(C(=CC(=C1N)N)N)N.Cl.Cl.Cl.Cl

InChi: InChI=1S/C6H10N4.4ClH/c7-3-1-4(8)6(10)2-5(3)9;;;;/h1-2H,7-10H2;4*1H

InChi Key: BZDGCIJWPWHAOF-UHFFFAOYSA-N