Z-FA-FMK | 1986

Cell-permeable. A useful negative control for FMK-labeled caspase inhibitors. Also, an irreversible inhibitor of cathepsins B, L, and S, and likely cathepsin H, as well as cruzain and papain.

Z-FA-FMK is a useful negative control for FMK-labeled caspase inhibitors. Also, an irreversible inhibitor of cathepsins B, L, and S, and likely cathepsin H, as well as cruzain and papain.

1986 | Z-FA-FMK DataSheet

Alternate Name/Synonyms: Benzyloxycarbonyl-Phe-Ala-Fluoromethylketone; Z-Phe-Ala fluoromethyl ketone; Z-Phe-Ala-FMK

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 105637-38-5

Structure Available?: Yes

Peptide sequence: Z-FA-FMK

Salt Form: No

Molecular Formula: C₂₁H₂₃N₂O₄F

Molecular Weight: 386.42

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (20 mM)

Handling: Protect from light and mositure

Country of Origin: USA

Tag Line: Anirreversible inhibitor of cathepsins B, L, and S

MDL Number: MFCD00883668

PubChem CID: 122019

SMILES: CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2

InChi: InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16) 24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)

InChi Key: ASXVEBPEZMSPHB-UHFFFAOYSA-N