Zalcitabine | B2796

Zalcitabine is an antiviral pyrimidine nucleoside analog effective against HIV replication. In cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered

Zalcitabine is an antiviral pyrimidine nucleoside analog effective against HIV replication. In cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered.

B2796 | Zalcitabine DataSheet

Alternate Name/Synonyms: 2′,3′-Dideoxycytidine,ddC,Hivid,NSC-606170,Ro 24-2027/000

Appearance: White to off-white solid

Formulation:

CAS Number: 7481-89-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₃N₃O₃

Molecular Weight: 211.22

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~0.2 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An antiviral agent

MDL Number: MFCD00012188

PubChem CID: 24066

SMILES: C1CC(OC1CO)N2C=CC(=NC2=O)N

InChi: InChI=1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1

InChi Key: WREGKURFCTUGRC-POYBYMJQSA-N