Zaprinast | 1715

Cell-permeable. A selective inhibitor of cGMP-specific phosphodiesterase (PDE V) (IC₅₀ = 0.45 µM). Inhibits PDE IX only at higher concentrations (IC₅₀ = 35 µM).

Zaprinast is a selective inhibitor of cGMP-specific phosphodiesterase (PDE V) (IC₅₀ = 0.45 µM). Inhibits PDE IX only at higher concentrations (IC₅₀ = 35 µM).

1715 | Zaprinast DataSheet

Alternate Name/Synonyms: 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one; M&B 22948

Appearance: White solid

Formulation: N/A

CAS Number: 37762-06-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₁₃N₅O₂

Molecular Weight: 271.27

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (100 mM)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A PDE V inhibitor

MDL Number: MFCD00214073

PubChem CID: 5722

SMILES: CCCOC1=CC=CC=C1C2=NC(=O)C3=NNNC3=N2

InChi: InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)

InChi Key: REZGGXNDEMKIQB-UHFFFAOYSA-N