ZCL278 | 2466

Cell-permeable. A selective CDc42 GTPase inhibitor. It specifically targets Cdc42-ITSN interaction and inhibits Cdc42-mediated cellular processes; could be a valuable tool to explore Cdc42’s involvement in cell motility and other actin-based cellular functions.

ZCL278 is a selective CDc42 GTPase inhibitor

2466 | ZCL278 DataSheet

Alternate Name/Synonyms: 2-(4-Bromo-2-chlorophenoxy)-N-[[[4-​[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]pheny​-l]amino]thioxomethyl]acetamide

Appearance: Yellow solid

Formulation: N/A

CAS Number: 587841-73-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₁₉BrClN₅O₄S₂

Molecular Weight: 584.89

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (> 50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective CDc42 GTPase inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(NC(NC1=CC=C(S(NC2=NC(C)=CC(C)=N2)(=O)=O)C=C1)=S)COC3=C(Cl)C=C(Br)C=C3

InChi: InChI=1S/C21H19BrClN5O4S2/c1-12-9-13(2)25-20(24-12)28-34(30,31)16-6-4-15(5-7-16)26-21(33)27-19(29)11-32-18-8-3-14(22)10-17(18)23/h3-10H,11H2,1-2H3,(H,24,25,28)(H2,26,27,29,33)

InChi Key: XKZDWYDHEBCGCG-UHFFFAOYSA-N