Zebularine | 2225

Zebularine is a potent inhibitor of cytidine deaminase and DNA methylation; inhjbits DNA methylation by forming a covalent complex with DNA methyltransferases (DNMTs). Displays antitumor properties.

Zebularine is a potent inhibitor of cytidine deaminase and DNA methylation.

2225 | Zebularine DataSheet

Alternate Name/Synonyms: 1H-​β-​D-​ribofuranosyl-​2-​pyrimidinone; NSC 309132

Appearance: White solid

Formulation: N/A

CAS Number: 3690-10-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₂N₂O₅

Molecular Weight: 228.2

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (100 mM) or H2O (100 mM)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A DNA methylation inhibitor

MDL Number: MFCD04973699

PubChem CID: 100016

SMILES: C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O

InChi: InChI=1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1

InChi Key: RPQZTTQVRYEKCR-WCTZXXKLSA-N