Zileuton | B2314

A potent and reversible 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC₅₀ values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively).

Zileuton is a potent and reversible 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC₅₀ values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively).

B2314 | Zileuton DataSheet

Alternate Name/Synonyms: N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea

Appearance: White solid

Formulation:

CAS Number: 111406-87-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₁H₁₂N₂O₂S

Molecular Weight: 236.29

Cell-Permeable?:

Purity: ≥98% HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and reversible 5-lipoxygenase (5-LOX) inhibitor

MDL Number: MFCD00866097

PubChem CID: 60490

SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O

InChi: InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)

InChi Key: MWLSOWXNZPKENC-UHFFFAOYSA-N