Description
A potent and reversible 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC₅₀ values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively).
Zileuton is a potent and reversible 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC₅₀ values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively).
Alternate Name/Synonyms: N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea
Appearance: White solid
Formulation:
CAS Number: 111406-87-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₁H₁₂N₂O₂S
Molecular Weight: 236.29
Cell-Permeable?:
Purity: ≥98% HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and reversible 5-lipoxygenase (5-LOX) inhibitor
MDL Number: MFCD00866097
PubChem CID: 60490
SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O
InChi: InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
InChi Key: MWLSOWXNZPKENC-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |