14-3-3 α/β polyclonal Antibody | BS90005

14-3-3 α/β polyclonal Antibody | BS90005 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC IP FC

Application Range: WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation among many other functions.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: 14-3-3 α/β polyclonal Antibody detects endogenous levels of 14-3-3 α/β protein.

Molecular Weight: 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: KCIP-1, YWHAB, 14 3 3 alpha, 14 3 3 protein beta/alpha, 14-3-3 protein beta/alpha, 1433B, Brain protein 14 3 3 beta isoform, GW128, HS 1, KCIP-1, KCIP1, N-terminally processed, Protein 1054, Protein kinase C inhibitor protein 1, YWHAA, YWHAB,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: