2',3',5'-triacetyl-5-Azacytidine | B2822

2',3',5'-triacetyl-5-Azacytidine is an oral prodrug form of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase, which can reverse epigenetically silenced genes. 2',3',5'-triacetyl-5-Azacytidine inhibits methylation and improves life expectancies in murine L1210 lymphocytic leukemia models.

2',3',5'-triacetyl-5-Azacytidine is an oral prodrug form of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase, which can reverse epigenetically silenced genes. 2',3',5'-triacetyl-5-Azacytidine inhibits methylation and improves life expectancies in murine L1210 lymphocytic leukemia models.

B2822 | 2',3',5'-triacetyl-5-Azacytidine DataSheet

Alternate Name/Synonyms: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)oxolan-2-yl]methyl acetate, (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate, 4-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one

Appearance: Crystalline solid

Formulation:

CAS Number: 10302-78-0

Structure Available?: True

Peptide sequence:

Salt Form: False

Molecular Formula: C₁₄H₁₈N₄O₈

Molecular Weight: 370.31

Cell-Permeable?: True

Purity: ≥95%

Solubilities: ~30 mg/ml in ethanol, DMSO and DMF in 0, ~10 mg/ml in PBS, pH 7.2 in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A prodrug and inhibitor of DNA methyl transferase

MDL Number: MFCD11113159

PubChem CID: 24864108

SMILES: CC(=O)OCC1C(C(C(O1)N2C=NC(=NC2=O)N)OC(=O)C)OC(=O)C

InChi: InChI=1S/C14H18N4O8/c1-6(19)23-4-9-10(24-7(2)20)11(25-8(3)21)12(26-9)18-5-16-13(15)17-14(18)22/h5,9-12H,4H2,1-3H3,(H2,15,17,22)/t9-,10-,11-,12-/m1/s1

InChi Key: OTQJVHISAFFLMA-DDHJBXDOSA-N