Description
2-Bromopalmitic acid is a fatty acid oxidation inhibitor. It inhibits carnitine palmitoyltransferase-1 (CPT1) and is also an inhibitor of protein palmitoylation. It significantly increases retinoic acid receptor alpha (RARα) protein level at a concentration of 5 μM. It overcomes all-trans retinoic acid (ATRA) resistance in acute promyelocytic leukemia.
2-Bromopalmitic acid is a fatty acid oxidation inhibitor. It inhibits carnitine palmitoyltransferase-1 (CPT1) and is also an inhibitor of protein palmitoylation. It significantly increases retinoic acid receptor alpha (RARα) protein level at a concentration of 5 μM. It overcomes all-trans retinoic acid (ATRA) resistance in acute promyelocytic leukemia.
B3128 | 2-Bromopalmitic acid DataSheet
Alternate Name/Synonyms: 2-Bromohexadecanoic acid
Appearance: White crystalline powder
Formulation:
CAS Number: 18263-25-7
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₁₆H₃₁BrO₂
Molecular Weight: 335.32
Cell-Permeable?: TRUE
Purity: ≥ 95%
Solubilities: ~100 mg/ml in methanol
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A fatty acid oxidation inhibitor
MDL Number: MFCD00004215
PubChem CID: 82145
SMILES: CCCCCCCCCCCCCCC(C(=O)O)Br
InChi: InChI=1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)
InChi Key: DPRAYRYQQAXQPE-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |