ABCB8 Polyclonal Antibody | E-AB-10118

ABCB8 Polyclonal Antibody | E-AB-10118 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ATP binding cassette sub family B member 8, ABCB8, ABCB8, ATP binding cassette sub family B (MDR/TAP) member 8, ATP binding cassette sub family B member 8 mitochondrial, ATP-binding cassette sub-family B member 8, EST328128, M ABC1, M-ABC1, MABC1, Mitochondrial ABC protein, mitochondrial, Mitochondrial ATP binding cassette 1, Mitochondrial ATP-binding cassette 1

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Concentration: 1.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human ABCB8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 80 kDa

Molecular Weight(Observed): N/A