ABCG1 Rabbit monoclonal Antibody | BS9916M

ABCG1 Rabbit monoclonal Antibody | BS9916M | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Application: WB ICC/IF IHC

Application Range: WB: 1:1000-1:2000 ICC/IF: 1:50-1:200 IHC: 1:50-1:200

Background: ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene. ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes. These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport. ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages. ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of ABCG1 and does not cross-react with related proteins.

Molecular Weight: ~ 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1

Immunogen: Recombinant Antibody.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified

Pathway: