ABI3BP polyclonal Antibody | BS72059

ABI3BP polyclonal Antibody | BS72059 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: TARSH [ABI family, member 3 (NESH) binding protein], whose alternative names include target of Nesh-SH3, Nesh-binding protein, ABI gene family member 3-binding protein, NESHBP, FLJ41743, FLJ41754 or ABI3BP, is a 1,075 amino acid protein involved in cellular senescence and tumor suppression. Loss of TARSH expression may play a role in the pathogenesis of cancer, especially in thyroid and lung. TARSH acts as a signal transduction molecule and is presumed to interact with with Abi-3, a protein involved in inhibition of ectopic metastasis of tumor cells. TARSH is expressed in brain, lung, heart, liver, placenta, pancreas and kidney, and four TARSH isoforms exist as a result of alternative splicing. TARSH contains a SH3 binding motif and a nuclear targeting sequence.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ABI3BP polyclonal Antibody detects endogenous levels of ABI3BP protein.

Molecular Weight: 118kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NESHBP; TARSH

Immunogen: Recombinant protein of human ABI3BP

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: