ACOT2 (T209) polyclonal Antibody | BS3060

ACOT2 (T209) polyclonal Antibody | BS3060 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT1 (acyl-CoA thioesterase 1, also known as CTE1) and ACOT2 (acyl-CoA thioesterase 2, also known as PTE2) are members of the ACOT family and exhibit different cellular localization, with ACOT1 existing as a monomer in the cytoplasm and ACOT2 localized primarily to mitochondria. Characteristic of most ACOT proteins, ACOT1 and ACOT2 catalyze the conversion of Palmitoyl-CoA and water to free CoA and palmitate, a reaction that is important for the regulation of intercellular fatty acid levels. ACOT2 is expressed as multiple alternatively spliced isoforms and, like ACOT1, is encoded by a gene which maps to human chromosome 14.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACOT2 (T209) polyclonal Antibody detects endogenous levels of ACOT2 protein.

Molecular Weight: ~ 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ACOT2; Acyl CoA thioesterase 2; Acyl coenzyme A thioester hydrolase 2a; Acyl coenzyme A thioesterase 2; mitochondrial; CTE Ia; CTE1A; Long chain acyl CoA thioesterase 2; Mitochondrial acyl CoA thioesterase 1; Mitochondrial acyl CoA thioesterase 2; MTE1; Peroxisomal long chain acyl coA; PTE2; PTE2A; ZAP128;

Immunogen: Synthetic peptide, corresponding to amino acids 180-230 of Human ACOT2.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A