ACPT Polyclonal Antibody | BS65947

ACPT Polyclonal Antibody | BS65947 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Horse,

Application: FCM,

Application Range: Flow-Cyt=0.2ug/test

Background: Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is upregulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. ACPT dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. ACPT is predominantly expressed in testis but exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACPT Polyclonal Antibody detects endogenous levels of ACPT protein.

Molecular Weight: 47kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Acid phosphatase testicular; Testicular acid phosphatase; PPAT_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human ACPT:65-160/437

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: