Actin-α/γ (Q49) polyclonal Antibody | BS1500

Actin-α/γ (Q49) polyclonal Antibody | BS1500 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background: Beta actin is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity.Be aware when using beta actin antibodies as loading controls that although beta actin is normally the best protein to use as a loading control, under some conditions its amounts can vary between samples. In particular, expression of actin in adipose tissue is very low (Spiegelman and Farmer, Cell, 1982, 29 (1) :53-60) "in cells undergoing adipose differentiation actin synthesis decreases by 90%".

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Actin-α/γ (Q49) polyclonal Antibody detects endogenous levels of Actin-α/γ protein.

Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Actin; alpha cardiac muscle 1; Alpha-cardiac actin; ACTC1; ACTC

Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Actin-α.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: PI3K AKT signaling,Translational Contral elF4 and p70 S6 Kinase,Insulin &Glucose Signaling,MTOR signaling,