Active EphB2 (Fc Tag), Human Recombinant | P1741

Active EphB2 (Fc Tag), Human Recombinant | P1741

Description: Ephrin Type-B Receptor 2 (EphB2) is a transmembrane receptor tyrosine kinase glycoprotein that functions through bidirectional signaling between adjacent cells. EphB2 functions in axon guidance during development, and also regulates development of dendrites and formation of synapses. EphB2 also controls angiogenesis, movement and adhesion of certain cells, and may function as a tumor suppressor. Some mutations of EphB2 have been associated with prostate and brain cancer.

Biomolecule/Target:

Synonyms: EPH Receptor B2; Developmentally-Regulated Eph-Related Tyrosine Kinase; Tyrosine-Protein Kinase Receptor EPH-3; Tyrosine-Protein Kinase TYRO5

Alternates names:

Taglines: Involved in axon guidance during development

NCBI Gene ID #: 2048

NCBI Gene Symbol: Human

Accession #: P29323

Recombinant: True

Source: Human cells

Purity by SDS-PAGE: > 90% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Activity (Specifications/test method):

Biological activity: Immobilized Active EphB2 (Fc Tag) 2 μg/ml (100 μl/well) can bind Ephrin B2

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 78.5 kDa (predicted); 120 kDa (observed)

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions:

Amino acid sequence: Val 19 to Ser 482 with C-terminal Fc Tag

Handling: Centrifuge the vial prior to opening.

Usage: