223

ACTR1A Antibody | 58-272

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SKU:
223-58-272-GEN
NULL705.00

Description

ACTR1A Antibody | 58-272 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Homology: Predicted species reactivity based on immunogen sequence: Monkey, Rat

Immunogen: This ACTR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human ACTR1A.

Research Area: Cell Cycle, Signal Transduction

Tested Application: WB

Application: For WB starting dilution is: 1:1000

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 43 kDa

Validation: N/A

Isoform: N/A

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality: Polyclonal

Clone: N/A

Isotype: Rabbit Ig

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration: batch dependent

Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog, ACTR1A, CTRN1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

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Additional Information

Size:
400 uL
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