ACTR1A polyclonal Antibody | BS6315

ACTR1A polyclonal Antibody | BS6315 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: The dynactin complex is a macromolecular complex that consists of 10-11 distinct subunits. This complex is critical for the function of dynein, a molecular motor protein. Dynactin plays a role in ER to Golgi transport, spindle formation, chromosome movement, axon guidance, nuclear positioning and the centripetal movement of lysosomes and endosomes. Centractin is a subunit of the dynactin complex that exists in multiple isoforms. The α isoform, also known as actin-related protein 1 homolog A (Arp1) and previously referred to as centractin, is the most abundant isoform in the dynactin complex. The β isoform, also known as actin-related protein 1 homolog B, shares 90% identity with the α isoform. The two isoforms, α and β, are expressed at a ratio of 15:1 respectively. The backbone filament structure of the dynactin complex (important for the arrangement of other complex proteins) is composed of 9-11 subunits of α/β-centractin.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACTR1A polyclonal Antibody detects endogenous levels of ACTR1A protein.

Molecular Weight: ~ 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Alpha-centractin; Centractin; ARP1; Actin-RPV; Centrosome-associated actin homolog; ACTR1A; CTRN1

Immunogen: Recombinant full length Human ACTR1A.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: