ACVR1B Polyclonal Antibody | E-AB-60969

ACVR1B Polyclonal Antibody | E-AB-60969 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction, Stem Cells

Background: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human ACVR1B (NP_004293.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 51 kDa/53 kDa/54 kDa/56 kDa/61 kDa

Molecular Weight(Observed): 49 kDa