ADAM12 Antibody | 23-294

ADAM12 Antibody | 23-294 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 589-738 of human ADAM12 (NP_067673.2) .

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: Mouse brain

Positive Control 2: Mouse thymus

Positive Control 3: Mouse fat

Positive Control 4: Mouse ovary

Positive Control 5: Rat brain

Positive Control 6: N/A

Molecular Weight: Observed: 100kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Adam12, OTTMUSP00000023508, Mltna, mKIAA4001, meltrin-alpha, meltrin alpha, KIAA4001, disintegrin and metalloproteinase domain-containing protein 12, ADAM 12, a disintegrin and metalloproteinase domain 12 (meltrin alpha) , a disintegrin and metalloprotease domain 12, a disintegrin and metallopeptidase domain 12 (meltrin alpha) , MLTN, UNQ346/PRO545

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.