ADAM17 polyclonal Antibody | BS90030

ADAM17 polyclonal Antibody | BS90030 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IP FC

Application Range: WB:1:1,000-1:2,000 FC:1:50-1:100 ICC:1:50-1:200 IP:1:50

Background: Tumor necrosis factor β (TNFβ), also known as lymphotoxin, is a pleiotropic cytokine. TNFα, also known as cachetin, is a cytokine that binds to the same receptors, producing an array of effects similar to those of TNFβ. TNFβ and TNFα share 30% amino acid homology and have similar biological activities. TNFβ is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNFα is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFβ and TNFα can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNFα converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNFα precursor to release soluble TNFα.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ADAM17 polyclonal Antibody detects endogenous levels of ADAM17 protein.

Molecular Weight: 93 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ADAM 17, A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), A disintegrin and metalloproteinase domain 17, ADA17, ADAM 17, ADAM metallopeptidase domain 17, ADAM17, ADAM17 protein, CD 156b, CD156b, CD156b antigen, CSVP, Disintegrin and metalloproteinase domain-containing protein 17, MGC71942, NISBD, NISBD1, Snake venom like protease, Snake venom-like protease, TACE, TNF alpha convertase, TNF alpha converting enzyme, TNF-alpha convertase, TNF-alpha-converting enzyme, Tumor Necrosis Factor Alpha Converting Enzyme,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: