ADAM23 Antibody | XW-7809

ADAM23 Antibody | XW-7809 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human

Homology: N/A

Immunogen: 72-144

Research Area: Other

Tested Application: WB

Application: ADAM 23 antibody can be used for the detection of ADAM 23 by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 91.9 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: ADAM23 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: MDC3, Disintegrin and metalloproteinase domain-containing protein 23, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3, ADAM 23, MDC3, MDC-3, A disintegrin and metalloproteinase domain 23

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.

SUBUNIT: Ligand for integrin α-V/γ-3.

SIMILARITY: Contains 1 peptidase M12B domain.

SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein (Potential) . Secreted protein. Isoform Gamma.

TISSUE SPECIFICITY: Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.

DEVELOPMENTAL STAGE: Highly expressed in the fetal brain.

DOMAIN:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.

SUMMARY: This protein is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is highly expressed in the brain and may function as an integrin ligand in the brain.