ADAM29 Antibody | 8183

ADAM29 Antibody | 8183 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: ADAM29 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ADAM29.
The immunogen is located within amino acids 710 - 760 of ADAM29.

Research Area: Homeostasis, Stem Cell

Tested Application: E, WB, IHC-P, IF

Application: ADAM29 antibody can be used for detection of ADAM29 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: ADAM29 antibody is human specific. ADAM29 antibody is predicted to not cross-react with other ADAM family proteins.

Positive Control 1: Cat. No. 1310 - Human Bladder Tissue Lysate

Positive Control 2: Cat. No. 11-701 - Human Testis Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 76 kDa
Observed: 80 kDa

Validation: N/A

Isoform: N/A

Purification: ADAM29 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ADAM29 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ADAM29 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Disintegrin and metalloproteinase domain-containing protein 29, ADAM metallopeptidase domain 29, CT73, SVPH1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The ADAM (a disintegrin and metalloprotease) protein family plays a role in cell-cell and cell-matrix interface related processes, including fertilization, muscle fusion, secretion of TNFalpha (tumor necrosis factor alpha) , and modulation of the neurogenic function of Notch and Delta (1-3) . ADAM29 contains one disintegrin domain, one EGF-like domain and one peptidase M12B domain (2) . It is highly expressed in testes (3) and may be involved in spermatogenesis and fertilization (4, 5) .