ADCY2 Antibody (Center) [APR03552G]

ADCY2 Antibody (Center) [APR03552G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-481 amino acids from the Central region of human ADCY2.

Cellular Localisation: Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm

Molecular Weight: 123603

Clone: Polyclonal

Gene Name: ADCY2

Gene ID: 108

Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642) . Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity) .

Summary: Tissue Location: Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699) . Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, ADCY2, KIAA1060