ADNP Antibody | 19-410

ADNP Antibody | 19-410 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 843-1102 of human ADNP (NP_056154.1) .

Research Area: Apoptosis, Cancer, Cell Cycle, Neuroscience

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: U-87MG

Positive Control 3: HT-29

Positive Control 4: Mouse liver

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 163kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.