Description
ADRA1A Antibody | 15-679 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human ADRA1A (NP_150646.3) .
Research Area: Apoptosis, Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: LO2
Positive Control 3: HL-60
Positive Control 4: Mouse heart
Positive Control 5: Mouse kidney
Positive Control 6: Mouse spinal cord
Molecular Weight: Observed: 51kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ADRA1A, adrenergic, alpha-1A-, receptor, ADRA1C, ADRA1L1, ALPHA1AAR, G protein coupled receptor, OTTHUMP00000125310, OTTHUMP00000125311, OTTHUMP00000125312, OTTHUMP00000125313, adrenergic, alpha-1A-, receptor variant 1, adrenergic, alpha-1A-, receptor var
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.