AF/LE Purified Anti-Human CD4 Monoclonal Antibody | DL21321F

AF/LE Purified Anti-Human CD4 Monoclonal Antibody | DL21321F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: T-cell surface glycoprotein CD4, CD4, T-cell surface antigen T4/Leu-3, CD4

Reactivity: Human

Application: Block, FCM, IHC, IF

Background: CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7) .

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: RPA-T4

Isotype: Mouse IgG1, κ