AF/LE Purified Anti-Human HLA-DR Monoclonal Antibody | DL21347F

AF/LE Purified Anti-Human HLA-DR Monoclonal Antibody | DL21347F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain, MHC class II antigen DRA, HLA-DRA1/DRB1, DRA/DRB1

Reactivity: Human

Application: Cell Sep-Neg, Block, Binding, FCM, WB, IHC, IP

Background: HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: L243

Isotype: Mouse IgG2a, κ