AF/LE Purified Anti-Human IL-4 Monoclonal Antibody | DL22178F

AF/LE Purified Anti-Human IL-4 Monoclonal Antibody | DL22178F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: Interleukin-4, IL-4, B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor

Reactivity: Human

Application: Neut, ICFCM, IHC

Background: IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: MP4-25D2

Isotype: Rat IgG1, κ