AF/LE Purified Anti-Mouse CD117 Antibody[2B8] | E-AB-F10920

AF/LE Purified Anti-Mouse CD117 Antibody[2B8] | E-AB-F10920 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117

Swissprot Code: P05532

Application: FCM, IHC, IF,IP

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2a, κ

Research Areas: Cancer, Developmental biology, Immunology, Neuroscience, Signal transduction, Stem cells, Tags & Cell Markers

Backgroun: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: 2B8

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A