Description
AF/LE Purified Anti-Mouse CD132 Antibody[3E12] | E-AB-F10150 | Gentaur UK, US & Europe Distribution
Category: Flowcytometry Antibody
Synonyms: Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132
Swissprot Code: P34902
Application: FCM,IP
Reactivity: Human,Mouse,Rat
Host: Mouse
Isotype: Mouse IgG1, κ
Research Areas: Immunology,Cancer
Backgroun: CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C. Do not freeze.
Immunogen: N/A
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Purification Method: N/A
Dilution: N/A
Clone: 3E12
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A