AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173] | E-AB-F11140

AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173] | E-AB-F11140 | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183/CXCR3

Swissprot Code: O88410

Application: FCM,Block

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2a, κ

Research Areas: Cancer, Cardiovascular, Immunology, Signal transduction

Backgroun: CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Purification Method: N/A

Dilution: N/A

Clone: CXCR3-173

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A