AF/LE Purified Anti-Mouse CD3 Monoclonal Antibody | DL20263F

AF/LE Purified Anti-Mouse CD3 Monoclonal Antibody | DL20263F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain, CD3E/D/G/Z, CD3e/d/g/z, CD3E/D/G/Z, CD3

Reactivity: Mouse

Application: FCM, IHC-F, IP, ICC

Background: CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: 17A2

Isotype: Rat IgG2b, κ