AF/LE Purified Anti-Mouse CD90.2 Monoclonal Antibody | DL21080F

AF/LE Purified Anti-Mouse CD90.2 Monoclonal Antibody | DL21080F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: Thy-1.2 membrane glycoprotein, Thy1.2, Thy-1.2 antigen, CD90.2, Thy-1.2

Reactivity: Mouse

Application: Depletion, FCM, IHC

Background: CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-) . CD90.2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

Concentration: 0.2 mg/mL

Conjugation: None (Purified antibody, Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.

Clone: 30H12

Isotype: Rat IgG2b, κ