AF488 Anti-Human CD45RO Antibody[UCHL1] | E-AB-F1139L

AF488 Anti-Human CD45RO Antibody[UCHL1] | E-AB-F1139L | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: N/A

Swissprot Code: P08575

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Research Areas: Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction, Stem cells

Backgroun: CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: UCHL1

Conjugation: AF488

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A