AF488 Anti-Mouse CD45 Antibody[30-F11] | E-AB-F1136UL

AF488 Anti-Mouse CD45 Antibody[30-F11] | E-AB-F1136UL | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45

Swissprot Code: P06800

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG2a, κ

Research Areas: Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction, Stem cells

Backgroun: CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: 30-F11

Conjugation: AF488

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A