Description
AF647 Anti-Mouse CD117 Antibody[2B8] | E-AB-F1092UM | Gentaur UK, US & Europe Distribution
Category: Flowcytometry Antibody
Synonyms: Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117
Swissprot Code: P05532
Application: FCM
Reactivity: Mouse
Host: Rat
Isotype: Rat IgG2b, κ
Research Areas: Cancer, Developmental biology, Immunology, Neuroscience, Signal transduction, Stem cells, Tags & Cell Markers
Backgroun: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: 2B8
Conjugation: AF647
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A