AF647 Anti-Mouse CD49b Antibody[DX5] | E-AB-F1116UM

AF647 Anti-Mouse CD49b Antibody[DX5] | E-AB-F1116UM | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Integrin alpha-2,CD49 antigen-like family member B,Collagen receptor,Platelet membrane glycoprotein Ia,GPIa,VLA-2 subunit alpha,CD49b

Swissprot Code: Q62469

Application: FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2b, κ

Research Areas: Immunology,Signal Transduction

Backgroun: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: DX5

Conjugation: AF647

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A