AF647 Anti-Mouse CD62L Antibody[Mel14] | E-AB-F1011UM

AF647 Anti-Mouse CD62L Antibody[Mel14] | E-AB-F1011UM | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22

Swissprot Code: P18337

Application: FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2b, κ

Research Areas: Cancer, Cardiovascular, Immunology, Stem cells

Backgroun: CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and nave T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish nave, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: Mel14

Conjugation: AF647

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A