AFP Antibody | 16-742

AFP Antibody | 16-742 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human AFP.

Research Area: Cancer, Cell Cycle, Stem Cell

Tested Application: WB, IF, IP

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: Mouse liver

Positive Control 3: Mouse kidney

Positive Control 4: Rat plasma

Positive Control 5: Rat liver

Positive Control 6: N/A

Molecular Weight: Observed: 75kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: AFP Antibody: FETA, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.