Description
AFP Antibody | XW-7017 | Gentaur UK, US & Europe Distribution
Host: Chicken
Reactivity: Human
Homology: N/A
Immunogen: 180-420
Research Area: Signal Transduction, Stem Cell
Tested Application: WB
Application: AFP antibody can be used for the detection of AFP by Western blot, may also work for IHC and ICC.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 68.7 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Antigen affinity-purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: AFP antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein, FETA, HPAFP,
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: α-1-fetoprotein. α-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. α-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of α-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.